|Description: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialprecursor (EC 220.127.116.11) (dUTPase) (dUTP pyrophosphatase).|
Ensembl ID: ENSG00000128951
UniprotKB/SwissProt: DUT_HUMAN (P33316)
Function: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Isoform DUT-N: Nucleus. Isoform DUT-M: Mitochondrion.