Regulatory Network in Protein Phosphorylation
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Substrate: ECT2

Description: Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene).

Ensembl ID: ENSG00000114346

UniprotKB/SwissProt: ECT2_HUMAN (Q9H8V3)

Function: Binds highly specifically to RhoA, RhoC and Rac proteins, but does not appear to catalyze guanine nucleotide exchange (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ECT2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ECT2ECT2_HUMANT328YEKAN T PELKK 24.01% Swiss-Prot 55.0 View   
2ECT2ECT2_HUMANT342MLSLN T PNSNR 29.19%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
3ECT2ECT2_HUMANS411TKSSK S STPVP 41.20% Phospho.ELM 7.0View   
4ECT2ECT2_HUMANT413SSKSS T PVPSK 35.08%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
5ECT2ECT2_HUMANS417STPVP S KQSAR 43.49% Phospho.ELM 7.0View   
6ECT2ECT2_HUMANT815FSFSK T PKRAL 32.61%PLK1 HPRD:11860(in vitro)  ViewAnalyzing
7ECT2ECT2_HUMANT815FSFSK T PKRAL 32.61%CDC2 HPRD:11860(in vitro)  ViewAnalyzing
8ECT2ECT2_HUMANT815FSFSK T PKRAL 32.61%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing