|Description: Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1)(CDC20-like protein 1).|
Synonyms: CDH1, FYR, FZR, KIAA1242
Ensembl ID: ENSG00000105325
UniprotKB/SwissProt: FZR_HUMAN (Q9UM11)
Function: Regulates ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. The APC/C-Cdh1 dimeric complex is activated during anaphase and telophase and remains active in degrading substrates until onset of the next S phase.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Isoform 2: Nucleus. Isoform 3: Cytoplasm.