Regulatory Network in Protein Phosphorylation
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Substrate: GFAP

Description: Glial fibrillary acidic protein (GFAP).

Ensembl ID: ENSG00000131095

UniprotKB/SwissProt: GFAP_HUMAN (P14136)

Function: GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Note=Associated with intermediate filaments.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GFAP

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GFAPGFAP_HUMANT7ERRRI T SAARR 15.53%AurB(Aurora B) Phospho.ELM 7.0 ViewAnalyzing
2GFAPGFAP_HUMANT7ERRRI T SAARR 15.53%ROCK1 Phospho.ELM 7.0  ViewAnalyzing
3GFAPGFAP_HUMANT7ERRRI T SAARR 15.53%ROCK1 HPRD:00675(in vitro;in vivo)  ViewAnalyzing
4GFAPGFAP_HUMANT7ERRRI T SAARR 15.53%ROCK_group Phospho.ELM 7.0 ViewAnalyzing
5GFAPGFAP_HUMANS8RRRIT S AARRS 19.98%CDC2 HPRD:00675(in vitro;in vivo)  ViewAnalyzing
6GFAPGFAP_HUMANS8RRRIT S AARRS 19.98%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
7GFAPGFAP_HUMANS13SAARR S YVSSG 25.08%ROCK1 Phospho.ELM 7.0