|Description: DNA-binding protein inhibitor ID-3 (Inhibitor of DNA binding 3) (ID-like protein inhibitor HLH 1R21) (Helix-loop-helix protein HEIR-1).|
Synonyms: 1R21, HEIR-1
Ensembl ID: ENSG00000117318
UniprotKB/SwissProt: ID3_HUMAN (Q02535)
Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.