Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinase CDK2]
Substrate: ITPR1

Description: Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform1) (InsP3R1) (IP3R).

Synonyms: INSP3R1

Ensembl ID: ENSG00000150995

UniprotKB/SwissProt: ITPR1_HUMAN (Q14643)

Function: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ITPR1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ITPR1ITPR1_HUMANY353QEKMV Y SLVSV 7.87%Fyn Phospho.ELM 7.0  ViewAnalyzing
2ITPR1ITPR1_HUMANY353QEKMV Y SLVSV 7.87%FYN HPRD:00925(in vitro)  ViewAnalyzing
3ITPR1ITPR1_HUMANS421LKIGT S PVKED 23.60%CDC2 HPRD:00925(in vivo)  ViewAnalyzing
4ITPR1ITPR1_HUMANS421LKIGT S PVKED 23.60%CDC2 HPRD:00925(in vitro;in vivo)  ViewAnalyzing
5ITPR1ITPR1_HUMANY482LEDLV Y FVTGG 10.30% Swiss-Prot 55.0 (Potential)View   
6ITPR1ITPR1_HUMANT800PQEQV T PVKYA 23.27%CDC2 HPRD:00925(in vitro;in vivo)  ViewAnalyzing
7ITPR1ITPR1_HUMANS1598AARRD S VLAAS 19.74% Swiss-Prot 55.0 View   
8ITPR1ITPR1_HUMANS1598AARRD S VLAAS 19.74%PKACa HPRD:00925(in vitro)  ViewAnalyzing
9ITPR1ITPR1_HUMANS1598AARRD S VLAAS 19.74% Phospho.ELM 7.0View   
10ITPR1ITPR1_HUMANS1764SGRRE S LTSFG 34.83%PKG1 HPRD:00925(in vitro;in vivo)  ViewAnalyzing
11ITPR1ITPR1_HUMANS1764SGRRE S LTSFG 34.83%PKA_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
12ITPR1ITPR1_HUMANS1764SGRRE S LTSFG 34.83%PKACa HPRD:00925(in vitro;in vivo)  ViewAnalyzing
13ITPR1ITPR1_HUMANY2664KDSTE Y TGPES 19.65% Swiss-Prot 55.0 (Potential)View