Regulatory Network in Protein Phosphorylation
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Substrate: KRT8

Description: Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8)(K8).

Synonyms: CYK8

Ensembl ID: ENSG00000170421

UniprotKB/SwissProt: K2C8_HUMAN (P05787)

Function: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of KRT8

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1KRT8K2C8_HUMANS9RVTQK S YKVST 21.99% Swiss-Prot 55.0 (Similarity)View   
2KRT8K2C8_HUMANS13KSYKV S TSGPR 16.83% Swiss-Prot 55.0 (Similarity)View   
3KRT8K2C8_HUMANS21GPRAF S SRSYT 24.69% Swiss-Prot 55.0 View   
4KRT8K2C8_HUMANS21GPRAF S SRSYT 24.69% HPRD:01015(in vivo)View   
5KRT8K2C8_HUMANS21GPRAF S SRSYT 24.69% Phospho.ELM 7.0View   
6KRT8K2C8_HUMANS22PRAFS S RSYTS 20.84% Swiss-Prot 55.0 View   
7KRT8K2C8_HUMANS22PRAFS S RSYTS 20.84%