Regulatory Network in Protein Phosphorylation
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Substrate: MCM4

Description: DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

Synonyms: CDC21

Ensembl ID: ENSG00000104738

UniprotKB/SwissProt: MCM4_HUMAN (P33991)

Function: Involved in the control of DNA replication.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (By similarity).
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of MCM4

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1MCM4MCM4_HUMANS3---MS S PASTP 24.16% HPRD:09094(in vitro)View   
2MCM4MCM4_HUMANS3---MS S PASTP 24.16%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
3MCM4MCM4_HUMANS3---MS S PASTP 24.16%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
4MCM4MCM4_HUMANT7SSPAS T PSRRG 27.65%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
5MCM4MCM4_HUMANT7SSPAS T PSRRG 27.65%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
6MCM4MCM4_HUMANT7SSPAS T PSRRG 27.65%CDC2 HPRD:09094(in vivo)  ViewAnalyzing
7MCM4MCM4_HUMANT7SSPAS T PSRRG 27.65% Phospho.ELM 7.0View   
8MCM4MCM4_HUMANT7SSPAS T PSRRG 27.65% HPRD:09094(in vitro)View   
9MCM4MCM4_HUMANT19RRGRA T PAQTP 20.14%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
10MCM4MCM4_HUMANT19RRGRA T PAQTP 20.14% Swiss-Prot 55.0 View   
11MCM4MCM4_HUMANT19RRGRA T PAQTP 20.14%CDC2 HPRD:09094(in vivo)  ViewAnalyzing
12MCM4MCM4_HUMANT19RRGRA T PAQTP 20.14% HPRD:09094(in vitro)View   
13MCM4MCM4_HUMANT19RRGRA T PAQTP 20.14%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
14MCM4MCM4_HUMANS26AQTPR S EDARS 40.82% Swiss-Prot 55.0 View   
15MCM4MCM4_HUMANS32EDARS S PSQRR 24.02% HPRD:09094(in vitro)View   
16MCM4MCM4_HUMANS32EDARS S PSQRR 24.02% Swiss-Prot 55.0 View   
17MCM4MCM4_HUMANS32EDARS S PSQRR 24.02%CDK2 Phospho.ELM 7.0  ViewAnalyzing
18MCM4MCM4_HUMANS32EDARS S PSQRR 24.02%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
19MCM4MCM4_HUMANS32EDARS S PSQRR 24.02%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
20MCM4MCM4_HUMANS32EDARS S PSQRR 24.02%CDC2 HPRD:09094(in vivo)  ViewAnalyzing
21MCM4MCM4_HUMANS54QPMPT S PGVDL 17.49% HPRD:09094(in vitro)View   
22MCM4MCM4_HUMANS54QPMPT S PGVDL 17.49%CHK1 Phospho.ELM 7.0  ViewAnalyzing
23MCM4MCM4_HUMANS54QPMPT S PGVDL 17.49%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
24MCM4MCM4_HUMANS54QPMPT S PGVDL 17.49%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
25MCM4MCM4_HUMANS54QPMPT S PGVDL 17.49%CDK2 Phospho.ELM 7.0  ViewAnalyzing
26MCM4MCM4_HUMANS88DFDVS S PLTYG 24.63%CDC2 HPRD:09094(in vivo)  ViewAnalyzing
27MCM4MCM4_HUMANS105EGTPR S GVRGT 42.73% Swiss-Prot 55.0 View   
28MCM4MCM4_HUMANT110SGVRG T PVRQR 14.19%CDK2 Phospho.ELM 7.0  ViewAnalyzing
29MCM4MCM4_HUMANT110SGVRG T PVRQR 14.19%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
30MCM4MCM4_HUMANT110SGVRG T PVRQR 14.19%CDK2 HPRD:09094(in vitro;in vivo)  ViewAnalyzing
31MCM4MCM4_HUMANT110SGVRG T PVRQR 14.19%CDC2 HPRD:09094(in vivo)  ViewAnalyzing
32MCM4MCM4_HUMANT110SGVRG T PVRQR 14.19% HPRD:09094(in vitro)View   
33MCM4MCM4_HUMANT110SGVRG T PVRQR 14.19% Swiss-Prot 55.0 View   
34MCM4MCM4_HUMANS120RPDLG S AQKGL 34.52% Swiss-Prot 55.0 View   
35MCM4MCM4_HUMANS120RPDLG S AQKGL 34.52% Phospho.ELM 7.0View   
36MCM4MCM4_HUMANS131QVDLQ S DGAAA 45.36% Phospho.ELM 7.0View   
37MCM4MCM4_HUMANS131QVDLQ S DGAAA 45.36% Swiss-Prot 55.0 View   
38MCM4MCM4_HUMANS142EDIVA S EQSLG 25.85% Phospho.ELM 7.0View   
39MCM4MCM4_HUMANS142EDIVA S EQSLG 25.85% Swiss-Prot 55.0 View   
40MCM4MCM4_HUMANS145VASEQ S LGQKL 30.34% Phospho.ELM 7.0View   
41MCM4MCM4_HUMANS145VASEQ S LGQKL 30.34% Swiss-Prot 55.0 View   
42MCM4MCM4_HUMANS326RIAEP S VCGRC 22.88% Phospho.ELM 7.0View   
43MCM4MCM4_HUMANS326RIAEP S VCGRC 22.88% HPRD:09094(in vivo)View   
44MCM4MCM4_HUMANS326RIAEP S VCGRC 22.88% Swiss-Prot 55.0 View