Regulatory Network in Protein Phosphorylation
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Substrate: MPHOSPH1

Description: M-phase phosphoprotein 1 (MPP1) (Kinesin-related motor interactingwith PIN1) (Cancer/testis antigen 90) (CT90).

Synonyms: KRMP1

Ensembl ID: ENSG00000138182

UniprotKB/SwissProt: MPPH1_HUMAN (Q96Q89)

Function: Plus-end-directed motor enzyme that is required for completion of cytokinesis.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Localizes mainly in the nucleus during interphase although it is also detected in the cytoplasm without clear association with microtubules. A 2-3 fold expression increase is seen as cells progress from G1 to G2/M phase. During p
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of MPHOSPH1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1MPHOSPH1MPPH1_HUMANS303KMLRL S QDVKG 20.21% Swiss-Prot 55.0 (Similarity)View   
2MPHOSPH1MPPH1_HUMANS310DVKGY S FIKDL 29.21% Swiss-Prot 55.0 View   
3MPHOSPH1MPPH1_HUMANS321QWIQV S DSKEA 21.57% Swiss-Prot 55.0 View   
4MPHOSPH1MPPH1_HUMANS323IQVSD S KEAYR 25.53% Swiss-Prot 55.0 View   
5MPHOSPH1MPPH1_HUMANS488DTLNS S QEKLF 41.09% Swiss-Prot 55.0 View   
6MPHOSPH1MPPH1_HUMANS999TLDSV S QISNI 26.25% Swiss-Prot 55.0 View   
7MPHOSPH1MPPH1_HUMANS1071EIVKA S SKKSH 36.65% Swiss-Prot 55.0 View   
8MPHOSPH1MPPH1_HUMANS1072IVKAS S KKSHQ 49.30% Swiss-Prot 55.0 View   
9MPHOSPH1MPPH1_HUMANT1644HPGCT T PVTVK 21.60%CDC2 Swiss-Prot 55.0   ViewAnalyzing
10MPHOSPH1MPPH1_HUMANT1644HPGCT T PVTVK 21.60%CDC2 HPRD:09268(in vitro)  ViewAnalyzing
11MPHOSPH1MPPH1_HUMANT1644HPGCT T PVTVK 21.60%CDC2 HPRD:09268(in vivo)  ViewAnalyzing