Regulatory Network in Protein Phosphorylation
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Substrate: MYOD1

Description: Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

Synonyms: MYF3, MYOD

Ensembl ID: ENSG00000129152

UniprotKB/SwissProt: MYOD1_HUMAN (P15172)

Function: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of MYOD1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1MYOD1MYOD1_HUMANS5-MELL S PPLRD 36.78%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
2MYOD1MYOD1_HUMANT115RRKAA T MRERR 22.94%PKCa HPRD:01166(in vitro)  ViewAnalyzing
3MYOD1MYOD1_HUMANT115RRKAA T MRERR 22.94%PKC_group Phospho.ELM 7.0 ViewAnalyzing
4MYOD1MYOD1_HUMANS200DSDAS S PRSNC 26.50%CDK2 HPRD:01166(in vitro)  ViewAnalyzing
5MYOD1MYOD1_HUMANS200DSDAS S PRSNC 26.50%CDK_group Phospho.ELM 7.0 ViewAnalyzing
6MYOD1MYOD1_HUMANS200DSDAS S PRSNC 26.50%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing