|Description: Origin recognition complex subunit 1 (Replication control protein 1).|
Synonyms: ORC1, PARC1
Ensembl ID: ENSG00000085840
UniprotKB/SwissProt: ORC1_HUMAN (Q13415)
Function: Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.