|Description: Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1) (Plectin-11).|
Ensembl ID: ENSG00000178209
UniprotKB/SwissProt: PLEC1_HUMAN (Q15149)
Function: Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: