Regulatory Network in Protein Phosphorylation
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Substrate: PPP1CA

Description: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit(EC 3.1.3.16) (PP-1A).

Synonyms: PPP1A

Ensembl ID: ENSG00000172531

UniprotKB/SwissProt: PP1A_HUMAN (P62136)

Function: Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PPP1CA

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PPP1CAPP1A_HUMANT320GGRPI T PPRNS 29.89%CDK2 Phospho.ELM 7.0  ViewAnalyzing
2PPP1CAPP1A_HUMANT320GGRPI T PPRNS 29.89%CDK_group Phospho.ELM 7.0 ViewAnalyzing
3PPP1CAPP1A_HUMANT320GGRPI T PPRNS 29.89%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing