Regulatory Network in Protein Phosphorylation
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Substrate: RAP1GAP

Description: Rap1 GTPase-activating protein 1 (Rap1GAP1) (Rap1GAP).

Synonyms: RAP1GA1

UniprotKB/SwissProt: RPGP1_HUMAN (P47736)

Function: GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus membrane; Peripheral membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RAP1GAP

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RAP1GAPRPGP1_HUMANS484IVPGK S PTRKK 37.10%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
2RAP1GAPRPGP1_HUMANS484IVPGK S PTRKK 37.10%CDC2 HPRD:02609(in vitro)  ViewAnalyzing
3RAP1GAPRPGP1_HUMANS490PTRKK S GPFGS 55.52%PKA_group Phospho.ELM 7.0 ViewAnalyzing
4RAP1GAPRPGP1_HUMANS490PTRKK S GPFGS 55.52%PKACa HPRD:02609(in vitro)  ViewAnalyzing
5RAP1GAPRPGP1_HUMANS499GSRRS S AIGIE 23.30%PKA_group Phospho.ELM 7.0 ViewAnalyzing
6RAP1GAPRPGP1_HUMANS499GSRRS S AIGIE 23.30%PKACa HPRD:02609(in vitro)  ViewAnalyzing
7RAP1GAPRPGP1_HUMANS525QKTPD S GHVSQ 31.81%GSK3B(GSK3 beta) Phospho.ELM 7.0 ViewAnalyzing