|Description: Regulator of chromosome condensation (Chromosome condensation protein1) (Cell cycle regulatory protein).|
Ensembl ID: ENSG00000180198
UniprotKB/SwissProt: RCC1_HUMAN (P18754)
Function: Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Becomes dispersed throughout the cytoplasm during mitosis.