|Description: Response gene to complement 32 protein (RGC-32).|
Ensembl ID: ENSG00000102760
UniprotKB/SwissProt: RGC32_HUMAN (Q9H4X1)
Function: Modulates the activity of cell cycle-specific kinases. Enhances CDC2 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase.