Regulatory Network in Protein Phosphorylation
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Substrate: RGC32

Description: Response gene to complement 32 protein (RGC-32).

Synonyms: C13orf15

Ensembl ID: ENSG00000102760

UniprotKB/SwissProt: RGC32_HUMAN (Q9H4X1)

Function: Modulates the activity of cell cycle-specific kinases. Enhances CDC2 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RGC32

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RGC32RGC32_HUMANS9PAAQG S PAAAA 10.17% Swiss-Prot 55.0 View   
2RGC32RGC32_HUMANS9PAAQG S PAAAA 10.17% Phospho.ELM 7.0View   
3RGC32RGC32_HUMANS29AAEDL S DALCE 32.91% Swiss-Prot 55.0 View   
4RGC32RGC32_HUMANS29AAEDL S DALCE 32.91% Phospho.ELM 7.0View   
5RGC32RGC32_HUMANS44LADFA S PFHER 28.26% Swiss-Prot 55.0 View   
6RGC32RGC32_HUMANS44LADFA S PFHER 28.26% Phospho.ELM 7.0View   
7RGC32RGC32_HUMANT111LSATV T PQKAK 18.69%CDC2 Swiss-Prot 55.0   ViewAnalyzing