Regulatory Network in Protein Phosphorylation
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Substrate: SYN3

Description: Synapsin-3 (Synapsin III).

Ensembl ID: ENSG00000185666

UniprotKB/SwissProt: SYN3_HUMAN (O14994)

Function: May be involved in the regulation of neurotransmitter release and synaptogenesis.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.
PDB:2P0A
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of SYN3

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1SYN3SYN3_HUMANS462SQQRL S PQGQQ 19.84% Swiss-Prot 55.0 (Similarity)View   
2SYN3SYN3_HUMANS470GQQPL S PQSGS 27.81% Swiss-Prot 55.0 (Similarity)View   
3SYN3SYN3_HUMANS470GQQPL S PQSGS 27.81%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
4SYN3SYN3_HUMANS470GQQPL S PQSGS 27.81%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
5SYN3SYN3_HUMANS470GQQPL S PQSGS 27.81% HPRD:04083(in vitro)View   
6SYN3SYN3_HUMANS484QRSPG S PQLSR 16.92% Swiss-Prot 55.0 (Similarity)View