|Description: Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1-polypeptide 1) (DRTF1).|
UniprotKB/SwissProt: TFDP1_HUMAN (Q14186)
Function: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.