|Description: Ubiquitin-like modifier-activating enzyme 1 (Ubiquitin-activatingenzyme E1) (Protein A1S9).|
Synonyms: A1S9T, UBE1
UniprotKB/SwissProt: UBA1_HUMAN (P22314)
Function: Activates ubiquitin by first adenylating with ATP its carboxy-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: