Regulatory Network in Protein Phosphorylation
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Substrate: ABCA1

Description: ATP-binding cassette sub-family A member 1 (ATP-binding cassettetransporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol effluxregulatory protein).

Synonyms: ABC1, CERP

Ensembl ID: ENSG00000165029

UniprotKB/SwissProt: ABCA1_HUMAN (O95477)

Function: cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ABCA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ABCA1ABCA1_HUMANS1042MQRKL S VALAF 14.37%PKA_group Swiss-Prot 55.0  ViewAnalyzing
2ABCA1ABCA1_HUMANS1042MQRKL S VALAF 14.37%PKA_group Phospho.ELM 7.0 ViewAnalyzing
3ABCA1ABCA1_HUMANS1042MQRKL S VALAF 14.37%PKACa HPRD:02501(in vivo)  ViewAnalyzing
4ABCA1ABCA1_HUMANS1141ESSLS S CRNSS 23.53% Swiss-Prot 55.0 (Similarity)View   
5ABCA1ABCA1_HUMANS1147CRNSS S TVSYL 32.42% Swiss-Prot 55.0 (Similarity)View   
6ABCA1ABCA1_HUMANT1242YGISE T TLEEI 29.86%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
7ABCA1ABCA1_HUMANT1243GISET T LEEIF 28.28%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
8ABCA1ABCA1_HUMANS1255KVAEE S GVDAE 35.30%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
9ABCA1ABCA1_HUMANT1286CLRPF T EDDAA 40.98% Phospho.ELM 7.0View   
10ABCA1ABCA1_HUMANT1305PESRE T DLLSG 30.73% Phospho.ELM 7.0View   
11ABCA1ABCA1_HUMANS2054NKRKL S TAMAL 19.70%PKACa HPRD:02501(in vivo)  ViewAnalyzing
12ABCA1ABCA1_HUMANS2054NKRKL S TAMAL 19.70%PKA_group Swiss-Prot 55.0  ViewAnalyzing
13ABCA1ABCA1_HUMANS2054NKRKL S TAMAL 19.70%PKA_group Phospho.ELM 7.0 ViewAnalyzing