Regulatory Network in Protein Phosphorylation
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Substrate: AQP4

Description: Aquaporin-4 (AQP-4) (WCH4) (Mercurial-insensitive water channel)(MIWC).

Ensembl ID: ENSG00000171885

UniprotKB/SwissProt: AQP4_HUMAN (P55087)

Function: Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of AQP4

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1AQP4AQP4_HUMANS276QQTKG S YMEVE 23.90%CK2_group Phospho.ELM 7.0 ViewAnalyzing
2AQP4AQP4_HUMANS276QQTKG S YMEVE 23.90%CK2a1 HPRD:02631(in vitro)  ViewAnalyzing
3AQP4AQP4_HUMANS276QQTKG S YMEVE 23.90%CK2a2 HPRD:02631(in vitro)  ViewAnalyzing
4AQP4AQP4_HUMANS276QQTKG S YMEVE 23.90%CK2a1-rs HPRD:02631(in vitro)  ViewAnalyzing
5AQP4AQP4_HUMANS285VEDNR S QVETD 44.85%CK2_group Phospho.ELM 7.0 ViewAnalyzing
6AQP4AQP4_HUMANS285VEDNR S QVETD 44.85% Swiss-Prot 55.0 (Similarity)View   
7AQP4AQP4_HUMANS285VEDNR S QVETD 44.85%CK2a2 HPRD:02631(in vitro)  ViewAnalyzing
8AQP4AQP4_HUMANS285VEDNR S QVETD 44.85%CK2a1-rs HPRD:02631(in vitro)  ViewAnalyzing
9AQP4AQP4_HUMANS285VEDNR S QVETD 44.85%CK2a1 HPRD:02631(in vitro)  ViewAnalyzing
10AQP4AQP4_HUMANS316KGKDQ S GEVLS 47.24%CK2a1 HPRD:02631(in vitro)  ViewAnalyzing
11AQP4AQP4_HUMANS316KGKDQ S GEVLS 47.24%CK2_group Phospho.ELM 7.0 ViewAnalyzing
12AQP4AQP4_HUMANS316KGKDQ S GEVLS 47.24%CK2a2 HPRD:02631(in vitro)  ViewAnalyzing
13AQP4AQP4_HUMANS316KGKDQ S GEVLS 47.24%CK2a1-rs HPRD:02631(in vitro)  ViewAnalyzing
14AQP4AQP4_HUMANS321SGEVL S SV 33.94% Swiss-Prot 55.0 (Similarity)View