|Description: Calmodulin (CaM).|
Synonyms: CALM, CAM, CAM1
Ensembl ID: ENSG00000143933
UniprotKB/SwissProt: CALM_HUMAN (P62158)
Function: Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Spindle. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.