Regulatory Network in Protein Phosphorylation
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Substrate: CDC37

Description: Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targetingsubunit) (p50Cdc37).

Synonyms: CDC37A

Ensembl ID: ENSG00000105401

UniprotKB/SwissProt: CDC37_HUMAN (Q16543)

Function: Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CDC37

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CDC37CDC37_HUMANS13DHIEV S DDEDE 26.93%CK2a2 HPRD:05456(in vivo)  ViewAnalyzing
2CDC37CDC37_HUMANS13DHIEV S DDEDE 26.93%CK2_group Phospho.ELM 7.0 ViewAnalyzing
3CDC37CDC37_HUMANS13DHIEV S DDEDE 26.93%CK2a1 HPRD:05456(in vivo)  ViewAnalyzing
4CDC37CDC37_HUMANS13DHIEV S DDEDE 26.93% HPRD:05456(in vitro)View   
5CDC37CDC37_HUMANS13DHIEV S DDEDE 26.93%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
6CDC37CDC37_HUMANS13DHIEV S DDEDE 26.93%CK2a1-rs HPRD:05456(in vivo)  ViewAnalyzing
7CDC37CDC37_HUMANY298DPVEV Y ESLPE 6.06% Swiss-Prot 55.0 View   
8CDC37CDC37_HUMANY298DPVEV Y ESLPE 6.06% Phospho.ELM 7.0View