Regulatory Network in Protein Phosphorylation
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Substrate: DDIT3

Description: DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA-damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

Synonyms: CHOP, GADD153

Ensembl ID: ENSG00000175197

UniprotKB/SwissProt: DDIT3_HUMAN (P35638)

Function: Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of DDIT3

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1DDIT3DDIT3_HUMANS14SFGTL S SWELE 32.99%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
2DDIT3DDIT3_HUMANS14SFGTL S SWELE 32.99%CK2_group Phospho.ELM 7.0 ViewAnalyzing
3DDIT3DDIT3_HUMANS14SFGTL S SWELE 32.99%CK2a1 HPRD:00529(in vitro)  ViewAnalyzing
4DDIT3DDIT3_HUMANS14SFGTL S SWELE 32.99%CK2a1-rs HPRD:00529(in vitro)  ViewAnalyzing
5DDIT3DDIT3_HUMANS15FGTLS S WELEA 27.90%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
6DDIT3DDIT3_HUMANS15FGTLS S WELEA 27.90%CK2_group Phospho.ELM 7.0 ViewAnalyzing
7DDIT3DDIT3_HUMANS15FGTLS S WELEA 27.90%CK2a1 HPRD:00529(in vitro)  ViewAnalyzing
8DDIT3DDIT3_HUMANS15FGTLS S WELEA 27.90%CK2a1-rs HPRD:00529(in vitro)  ViewAnalyzing
9DDIT3DDIT3_HUMANS30LQEVL S SDENG 40.70%CK2a1 HPRD:00529(in vitro)  ViewAnalyzing
10DDIT3DDIT3_HUMANS30LQEVL S SDENG 40.70%CK2a1-rs HPRD:00529(in vitro)  ViewAnalyzing
11DDIT3DDIT3_HUMANS30LQEVL S SDENG 40.70%CK2_group Phospho.ELM 7.0 ViewAnalyzing
12DDIT3DDIT3_HUMANS31QEVLS S DENGG 44.79%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
13DDIT3DDIT3_HUMANS31QEVLS S DENGG 44.79%CK2a1-rs HPRD:00529(in vitro)  ViewAnalyzing
14DDIT3DDIT3_HUMANS31QEVLS S DENGG 44.79%CK2a1 HPRD:00529(in vitro)  ViewAnalyzing
15DDIT3DDIT3_HUMANS31QEVLS S DENGG 44.79%CK2_group Phospho.ELM 7.0 ViewAnalyzing
16DDIT3DDIT3_HUMANS79TSTSQ S PHSPD 25.09%p38_group Phospho.ELM 7.0 ViewAnalyzing
17DDIT3DDIT3_HUMANS79TSTSQ S PHSPD 25.09%p38a HPRD:00529(in vitro)  ViewAnalyzing
18DDIT3DDIT3_HUMANS82SQSPH S PDSSQ 33.51%p38_group Phospho.ELM 7.0 ViewAnalyzing
19DDIT3DDIT3_HUMANS82SQSPH S PDSSQ 33.51%p38a HPRD:00529(in vitro)  ViewAnalyzing