Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinase CK2a1]
Substrate: EGR1

Description: Early growth response protein 1 (EGR-1) (Protein Krox-24)(Transcription factor Zif268) (Nerve growth factor-induced protein A)(NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225)(AT225).

Synonyms: ZNF225

Ensembl ID: ENSG00000120738

UniprotKB/SwissProt: EGR1_HUMAN (P18146)

Function: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of EGR1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1EGR1EGR1_HUMANS378CMRNF S RSDHL 34.13%CK2a1 HPRD:00549(in vitro;in vivo)  ViewAnalyzing
2EGR1EGR1_HUMANS378CMRNF S RSDHL 34.13%CK2_group Phospho.ELM 7.0 ViewAnalyzing
3EGR1EGR1_HUMANS378CMRNF S RSDHL 34.13%CK2a1-rs HPRD:00549(in vitro;in vivo)  ViewAnalyzing
4EGR1EGR1_HUMANT391HIRTH T GEKPF 46.56%CK2a1 HPRD:00549(in vitro;in vivo)  ViewAnalyzing
5EGR1EGR1_HUMANT391HIRTH T GEKPF 46.56%CK2a1-rs HPRD:00549(in vitro;in vivo)  ViewAnalyzing
6EGR1EGR1_HUMANT526SFSAS T GLSDM 41.69%CK2a1 HPRD:00549(in vitro;in vivo)  ViewAnalyzing
7EGR1EGR1_HUMANT526SFSAS T GLSDM 41.69%CK2a1-rs HPRD:00549(in vitro;in vivo)  ViewAnalyzing