Regulatory Network in Protein Phosphorylation
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Substrate: GAP43

Description: Neuromodulin (Axonal membrane protein GAP-43) (Growth-associatedprotein 43) (PP46) (Neural phosphoprotein B-50).

Ensembl ID: ENSG00000172020

UniprotKB/SwissProt: NEUM_HUMAN (P17677)

Function: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GAP43

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GAP43NEUM_HUMANS41TKIQA S FRGHI 10.09% Swiss-Prot 55.0 (Similarity)View   
2GAP43NEUM_HUMANS41TKIQA S FRGHI 10.09%PKCb HPRD:01198(in vitro)  ViewAnalyzing
3GAP43NEUM_HUMANT94EAAPA T GSKPD 40.71% Swiss-Prot 55.0 (Similarity)View   
4GAP43NEUM_HUMANS96APATG S KPDEP 36.34% HPRD:01198(in vitro)View   
5GAP43NEUM_HUMANT181AAAAT T PAAED 13.25% Swiss-Prot 55.0 (Similarity)View   
6GAP43NEUM_HUMANS202TETGE S SQAEE 29.15%CK2a1-rs HPRD:01198(in vitro)  ViewAnalyzing
7GAP43NEUM_HUMANS202TETGE S SQAEE 29.15%CK2_group  Swiss-Prot 55.0 (Similarity) ViewAnalyzing
8GAP43NEUM_HUMANS202TETGE S SQAEE 29.15%CK2a1 HPRD:01198(in vitro)  ViewAnalyzing
9GAP43NEUM_HUMANS203ETGES S QAEEN 29.16%CK2_group  Swiss-Prot 55.0 (Similarity) ViewAnalyzing
10GAP43NEUM_HUMANS203ETGES S QAEEN 29.16%CK2a1 HPRD:01198(in vitro)  ViewAnalyzing
11GAP43NEUM_HUMANS203ETGES S QAEEN 29.16%CK2a1-rs HPRD:01198(in vitro)  ViewAnalyzing