Regulatory Network in Protein Phosphorylation
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Substrate: GTF2A1

Description: Transcription initiation factor IIA subunit 1 (General transcriptionfactor IIA1) (TFIIA-42) (TFIIAL) [Contains: Transcription initiationfactor IIA alpha chain (TFIIA p35 subunit); Transcription initiationfactor IIA beta chain (TFIIA p19 subunit)].

Synonyms: TF2A1

Ensembl ID: ENSG00000165417

UniprotKB/SwissProt: TF2AA_HUMAN (P52655)

Function: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
PDB:1NVP
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GTF2A1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%CK2a2 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
2GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%CK2a1-rs HPRD:02748(in vitro;in vivo)  ViewAnalyzing
3GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%CK2a1 HPRD:02748(in vivo)  ViewAnalyzing
4GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%CK2a1-rs HPRD:02748(in vivo)  ViewAnalyzing
5GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%CK2_group Phospho.ELM 7.0 ViewAnalyzing
6GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%TAF1 Swiss-Prot 55.0   ViewAnalyzing
7GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%CK2a1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
8GTF2A1TF2AA_HUMANS280GTGDT S SEEDE 40.26%TAF1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
9GTF2A1TF2AA_HUMANS281TGDTS S EEDED 47.28%CK2a1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
10GTF2A1TF2AA_HUMANS281TGDTS S EEDED 47.28%CK2a2 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
11GTF2A1TF2AA_HUMANS281TGDTS S EEDED 47.28%CK2a1-rs HPRD:02748(in vitro;in vivo)  ViewAnalyzing
12GTF2A1TF2AA_HUMANS281TGDTS S EEDED 47.28%CK2_group Phospho.ELM 7.0 ViewAnalyzing
13GTF2A1TF2AA_HUMANS281TGDTS S EEDED 47.28%TAF1 Swiss-Prot 55.0   ViewAnalyzing
14GTF2A1TF2AA_HUMANS281TGDTS S EEDED 47.28%TAF1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
15GTF2A1TF2AA_HUMANS316EEPLN S EDDVS 50.51%CK2a1-rs HPRD:02748(in vitro;in vivo)  ViewAnalyzing
16GTF2A1TF2AA_HUMANS316EEPLN S EDDVS 50.51%CK2a1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
17GTF2A1TF2AA_HUMANS316EEPLN S EDDVS 50.51%CK2_group Phospho.ELM 7.0 ViewAnalyzing
18GTF2A1TF2AA_HUMANS316EEPLN S EDDVS 50.51%CK2a2 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
19GTF2A1TF2AA_HUMANS316EEPLN S EDDVS 50.51%TAF1 Swiss-Prot 55.0   ViewAnalyzing
20GTF2A1TF2AA_HUMANS316EEPLN S EDDVS 50.51%TAF1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
21GTF2A1TF2AA_HUMANS321SEDDV S DEEGQ 46.42%TAF1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
22GTF2A1TF2AA_HUMANS321SEDDV S DEEGQ 46.42%CK2a2 HPRD:02748(in vitro;in vivo)  ViewAnalyzing
23GTF2A1TF2AA_HUMANS321SEDDV S DEEGQ 46.42%TAF1 Swiss-Prot 55.0   ViewAnalyzing
24GTF2A1TF2AA_HUMANS321SEDDV S DEEGQ 46.42%CK2a1-rs HPRD:02748(in vitro;in vivo)  ViewAnalyzing
25GTF2A1TF2AA_HUMANS321SEDDV S DEEGQ 46.42%CK2_group Phospho.ELM 7.0 ViewAnalyzing
26GTF2A1TF2AA_HUMANS321SEDDV S DEEGQ 46.42%CK2a1 HPRD:02748(in vitro;in vivo)  ViewAnalyzing