Regulatory Network in Protein Phosphorylation
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Substrate: HNRNPA1

Description: Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizingprotein) (Single-strand RNA-binding protein) (hnRNP core protein A1).

Synonyms: HNRPA1

Ensembl ID: ENSG00000135486

UniprotKB/SwissProt: ROA1_HUMAN (P09651)

Function: Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes.
PDB:1HA1
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of HNRNPA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1HNRNPA1ROA1_HUMANS2----M S KSESP 44.91% Phospho.ELM 7.0View   
2HNRNPA1ROA1_HUMANS4--MSK S ESPKE 35.68% Swiss-Prot 55.0 View   
3HNRNPA1ROA1_HUMANS4--MSK S ESPKE 35.68% Phospho.ELM 7.0View   
4HNRNPA1ROA1_HUMANS6MSKSE S PKEPE 48.65% Phospho.ELM 7.0View   
5HNRNPA1ROA1_HUMANS6MSKSE S PKEPE 48.65% HPRD:01242(in vivo)View   
6HNRNPA1ROA1_HUMANS6MSKSE S PKEPE 48.65% HPRD:01242(in vivo)View   
7HNRNPA1ROA1_HUMANS6MSKSE S PKEPE 48.65% Swiss-Prot 55.0 View   
8HNRNPA1ROA1_HUMANS91PKRAV S REDSQ 29.03% Swiss-Prot 55.0 View   
9HNRNPA1ROA1_HUMANS95VSRED S QRPGA 24.28% Swiss-Prot 55.0 View   
10HNRNPA1ROA1_HUMANT138VIEIM T DRGSG 28.36% Swiss-Prot 55.0 View   
11HNRNPA1ROA1_HUMANT138VIEIM T DRGSG 28.36% Phospho.ELM 7.0View   
12HNRNPA1ROA1_HUMANY167IVIQK Y HTVNG 6.07% Swiss-Prot 55.0 View   
13HNRNPA1ROA1_HUMANS192ASASS S QRGRS 22.77% Phospho.ELM 7.0View   
14HNRNPA1ROA1_HUMANS199RGRSG S GNFGG 31.63%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
15HNRNPA1ROA1_HUMANS199RGRSG S GNFGG 31.63%PKA_group Phospho.ELM 7.0 ViewAnalyzing
16HNRNPA1ROA1_HUMANS311FGGGG S YNDFG 24.84% Swiss-Prot 55.0 (Similarity)View   
17HNRNPA1ROA1_HUMANS338FGGRS S GPYGG 42.29% Swiss-Prot 55.0 View   
18HNRNPA1ROA1_HUMANY347GGGGQ Y FAKPR 14.58% Swiss-Prot 55.0 View   
19HNRNPA1ROA1_HUMANY347GGGGQ Y FAKPR 14.58% Phospho.ELM 7.0View   
20HNRNPA1ROA1_HUMANS362YGGSS S SSSYG 35.62% Phospho.ELM 7.0View   
21HNRNPA1ROA1_HUMANS363GGSSS S SSYGS 25.83% Phospho.ELM 7.0View   
22HNRNPA1ROA1_HUMANS364GSSSS S SYGSG 29.53% Phospho.ELM 7.0View