Regulatory Network in Protein Phosphorylation
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Substrate: HSP90AA1

Description: Heat shock protein HSP 90-alpha (HSP 86) (Renal carcinoma antigen NY-REN-38).

Synonyms: HSP90A, HSPC1, HSPCA

Ensembl ID: ENSG00000080824

UniprotKB/SwissProt: HS90A_HUMAN (P07900)

Function: Molecular chaperone. Has ATPase activity (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
PDB:1BYQ
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of HSP90AA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1HSP90AA1HS90A_HUMANT5-MPEE T QTQDQ 34.94%DNAPK HPRD:00777(in vitro)  ViewAnalyzing
2HSP90AA1HS90A_HUMANT5-MPEE T QTQDQ 34.94%DNAPK Swiss-Prot 55.0   ViewAnalyzing
3HSP90AA1HS90A_HUMANT5-MPEE T QTQDQ 34.94% Phospho.ELM 7.0View   
4HSP90AA1HS90A_HUMANT7PEETQ T QDQPM 41.34%DNAPK HPRD:00777(in vitro)  ViewAnalyzing
5HSP90AA1HS90A_HUMANT7PEETQ T QDQPM 41.34%DNAPK Phospho.ELM 7.0  ViewAnalyzing
6HSP90AA1HS90A_HUMANT7PEETQ T QDQPM 41.34%DNAPK Swiss-Prot 55.0   ViewAnalyzing
7HSP90AA1HS90A_HUMANS231RDKEV S DDEAE 40.20%CK2_group Phospho.ELM 7.0 ViewAnalyzing
8HSP90AA1HS90A_HUMANS231RDKEV S DDEAE 40.20%CK2a1 HPRD:00777(in vitro;in vivo)  ViewAnalyzing
9HSP90AA1HS90A_HUMANS231RDKEV S DDEAE 40.20% Swiss-Prot 55.0 View   
10HSP90AA1HS90A_HUMANS231RDKEV S DDEAE 40.20%CK2a1-rs HPRD:00777(in vitro;in vivo)  ViewAnalyzing
11HSP90AA1HS90A_HUMANS252KEEKE S EDKPE 63.26% Phospho.ELM 7.0View   
12HSP90AA1HS90A_HUMANS252KEEKE S EDKPE 63.26% Swiss-Prot 55.0 View   
13HSP90AA1HS90A_HUMANS263IEDVG S DEEEE 41.52% Swiss-Prot 55.0 View   
14HSP90AA1HS90A_HUMANS263IEDVG S DEEEE 41.52%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
15HSP90AA1HS90A_HUMANS263IEDVG S DEEEE 41.52%CK2_group Phospho.ELM 7.0 ViewAnalyzing
16HSP90AA1HS90A_HUMANS263IEDVG S DEEEE 41.52%CK2a1 HPRD:00777(in vitro;in vivo)  ViewAnalyzing
17HSP90AA1HS90A_HUMANS263IEDVG S DEEEE 41.52%CK2a1-rs HPRD:00777(in vitro;in vivo)  ViewAnalyzing
18HSP90AA1HS90A_HUMANY313EYGEF Y KSLTN 8.72% Swiss-Prot 55.0 (Similarity)View   
19HSP90AA1HS90A_HUMANY492NQKHI Y YITGE 6.63% Swiss-Prot 55.0 (Similarity)View