Regulatory Network in Protein Phosphorylation
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Substrate: KLF1

Description: Krueppel-like factor 1 (Erythroid krueppel-like transcription factor)(EKLF) (Erythroid transcription factor).

Synonyms: EKLF

Ensembl ID: ENSG00000105610

UniprotKB/SwissProt: KLF1_HUMAN (Q13351)

Function: Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Probably serves as a general switch factor for erythroid development.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of KLF1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1KLF1KLF1_HUMANT23GPFPD T QDDFL 33.85%PKACa HPRD:07197(in vitro;in vivo)  ViewAnalyzing
2KLF1KLF1_HUMANT23GPFPD T QDDFL 33.85%CK2_group Phospho.ELM 7.0 ViewAnalyzing