Regulatory Network in Protein Phosphorylation
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Substrate: L1CAM

Description: Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

Synonyms: CAML1, MIC5

Ensembl ID: ENSG00000198910

UniprotKB/SwissProt: L1CAM_HUMAN (P32004)

Function: Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Single-pass type I membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of L1CAM

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1L1CAML1CAM_HUMANS1152KGGKY S VKDKE 26.61%RSK3 HPRD:02394(in vitro;in vivo)  ViewAnalyzing
2L1CAML1CAM_HUMANS1152KGGKY S VKDKE 26.61%RSK1 HPRD:02394(in vitro)  ViewAnalyzing
3L1CAML1CAM_HUMANS1152KGGKY S VKDKE 26.61% Phospho.ELM 7.0View   
4L1CAML1CAM_HUMANS1163DTQVD S EARPM 34.01% Swiss-Prot 55.0 View   
5L1CAML1CAM_HUMANS1163DTQVD S EARPM 34.01% Phospho.ELM 7.0View   
6L1CAML1CAM_HUMANS1181YRSLE S DNEEK 51.54%CK2_group Phospho.ELM 7.0 ViewAnalyzing
7L1CAML1CAM_HUMANS1181YRSLE S DNEEK 51.54%CK2a1-rs HPRD:02394(in vitro)  ViewAnalyzing
8L1CAML1CAM_HUMANS1181YRSLE S DNEEK 51.54%CK2a1 HPRD:02394(in vitro)  ViewAnalyzing
9L1CAML1CAM_HUMANS1190EKAFG S SQPSL 21.24% Swiss-Prot 55.0 View   
10L1CAML1CAM_HUMANS1190EKAFG S SQPSL 21.24% Phospho.ELM 7.0View   
11L1CAML1CAM_HUMANS1191KAFGS S QPSLN 46.63% Phospho.ELM 7.0View   
12L1CAML1CAM_HUMANS1191KAFGS S QPSLN 46.63% Swiss-Prot 55.0 View   
13L1CAML1CAM_HUMANS1194GSSQP S LNGDI 27.16% Phospho.ELM 7.0View   
14L1CAML1CAM_HUMANS1194GSSQP S LNGDI 27.16% Swiss-Prot 55.0 View   
15L1CAML1CAM_HUMANT1247DSSGA T SPINP 38.26% Swiss-Prot 55.0 (Similarity)View   
16L1CAML1CAM_HUMANS1248SSGAT S PINPA 24.21% Swiss-Prot 55.0 (Similarity)View