Regulatory Network in Protein Phosphorylation
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Substrate: LGALS3

Description: Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-bindingprotein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35)(Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-bindingprotein) (GALBP).

Synonyms: MAC2

Ensembl ID: ENSG00000131981

UniprotKB/SwissProt: LEG3_HUMAN (P17931)

Function: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Note=Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface.
PDB:1A3K
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of LGALS3

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1LGALS3LEG3_HUMANS6MADNF S LHDAL 30.92% Swiss-Prot 55.0 View   
2LGALS3LEG3_HUMANS6MADNF S LHDAL 30.92%CK1a(CK1 alpha) Phospho.ELM 7.0 ViewAnalyzing
3LGALS3LEG3_HUMANS6MADNF S LHDAL 30.92%CK1a HPRD:01090(in vitro;in vivo)  ViewAnalyzing
4LGALS3LEG3_HUMANS6MADNF S LHDAL 30.92%CK2a2 HPRD:01090(in vitro;in vivo)  ViewAnalyzing
5LGALS3LEG3_HUMANS6MADNF S LHDAL 30.92%CK2a1-rs HPRD:01090(in vitro;in vivo)  ViewAnalyzing
6LGALS3LEG3_HUMANS6MADNF S LHDAL 30.92%CK2a1 HPRD:01090(in vitro;in vivo)  ViewAnalyzing
7LGALS3LEG3_HUMANS12LHDAL S GSGNP 32.41%CK2a1-rs HPRD:01090(in vitro;in vivo)  ViewAnalyzing
8LGALS3LEG3_HUMANS12LHDAL S GSGNP 32.41%CK2a1 HPRD:01090(in vitro;in vivo)  ViewAnalyzing
9LGALS3LEG3_HUMANS12LHDAL S GSGNP 32.41%CK2a2 HPRD:01090(in vitro;in vivo)  ViewAnalyzing
10LGALS3LEG3_HUMANS12LHDAL S GSGNP 32.41%CK1a HPRD:01090(in vitro;in vivo)  ViewAnalyzing
11LGALS3LEG3_HUMANS12LHDAL S GSGNP 32.41% Swiss-Prot 55.0 View   
12LGALS3LEG3_HUMANS12LHDAL S GSGNP 32.41%CK1a(CK1 alpha) Phospho.ELM 7.0 ViewAnalyzing