Regulatory Network in Protein Phosphorylation
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Substrate: MAX

Description: Protein max (Myc-associated factor X).

Ensembl ID: ENSG00000125952

UniprotKB/SwissProt: MAX_HUMAN (P61244)

Function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3-K9 histone methyltransferase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
PDB:1AN2
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of MAX

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1MAXMAX_HUMANS2----M S DNDDI 45.16% Swiss-Prot 55.0 View   
2MAXMAX_HUMANS2----M S DNDDI 45.16%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
3MAXMAX_HUMANS2----M S DNDDI 45.16%CK2_group Phospho.ELM 7.0 ViewAnalyzing
4MAXMAX_HUMANS2----M S DNDDI 45.16%CK2a1-rs HPRD:01113(in vitro;in vivo)  ViewAnalyzing
5MAXMAX_HUMANS2----M S DNDDI 45.16%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
6MAXMAX_HUMANS2----M S DNDDI 45.16%CK2a1 HPRD:01113(in vitro;in vivo)  ViewAnalyzing
7MAXMAX_HUMANS2----M S DNDDI 45.16%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
8MAXMAX_HUMANS11DIEVE S DEEQP 56.34%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
9MAXMAX_HUMANS11DIEVE S DEEQP 56.34%CK2a1-rs HPRD:01113(in vitro;in vivo)  ViewAnalyzing
10MAXMAX_HUMANS11DIEVE S DEEQP 56.34%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
11MAXMAX_HUMANS11DIEVE S DEEQP 56.34%CK2_group Phospho.ELM 7.0 ViewAnalyzing
12MAXMAX_HUMANS11DIEVE S DEEQP 56.34%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
13MAXMAX_HUMANS11DIEVE S DEEQP 56.34% Swiss-Prot 55.0 View   
14MAXMAX_HUMANS11DIEVE S DEEQP 56.34%CK2a1 HPRD:01113(in vitro;in vivo)  ViewAnalyzing
15MAXMAX_HUMANS49HSLRD S VPSLQ 29.50%p38a HPRD:01113(in vitro)  ViewAnalyzing
16MAXMAX_HUMANY123SDNSL Y TNAKG 9.58% Phospho.ELM 7.0View   
17MAXMAX_HUMANY123SDNSL Y TNAKG 9.58% Swiss-Prot 55.0 View   
18MAXMAX_HUMANS129TNAKG S TISAF 23.12%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
19MAXMAX_HUMANS129TNAKG S TISAF 23.12%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
20MAXMAX_HUMANS132KGSTI S AFDGG 23.99%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
21MAXMAX_HUMANS132KGSTI S AFDGG 23.99%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
22MAXMAX_HUMANS138AFDGG S DSSSE 39.59%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
23MAXMAX_HUMANS138AFDGG S DSSSE 39.59%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
24MAXMAX_HUMANS140DGGSD S SSESE 37.14%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
25MAXMAX_HUMANS140DGGSD S SSESE 37.14%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
26MAXMAX_HUMANS141GGSDS S SESEP 43.02%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
27MAXMAX_HUMANS141GGSDS S SESEP 43.02%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
28MAXMAX_HUMANS142GSDSS S ESEPE 49.44%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
29MAXMAX_HUMANS142GSDSS S ESEPE 49.44%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing
30MAXMAX_HUMANS144DSSSE S EPEEP 61.47%CK2a1-rs HPRD:01113(in vitro)  ViewAnalyzing
31MAXMAX_HUMANS144DSSSE S EPEEP 61.47%p38a HPRD:01113(in vitro)  ViewAnalyzing
32MAXMAX_HUMANS144DSSSE S EPEEP 61.47%CK2a1 HPRD:01113(in vitro)  ViewAnalyzing