Regulatory Network in Protein Phosphorylation
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Substrate: MAZ

Description: Myc-associated zinc finger protein (MAZI) (Purine-bindingtranscription factor) (Pur-1) (ZF87) (ZIF87).

Ensembl ID: ENSG00000103495

UniprotKB/SwissProt: MAZ_HUMAN (P56270)

Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (Probable). Note=In brains of Alzheimer disease patients, present in a plaque-like structures.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of MAZ

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1MAZMAZ_HUMANT72PAPPP T PQAPA 33.53%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
2MAZMAZ_HUMANS460AVGSL S GAEGV 37.34%CK2a1 HPRD:02999(in vitro;in vivo)  ViewAnalyzing
3MAZMAZ_HUMANS460AVGSL S GAEGV 37.34%CK2a1-rs HPRD:02999(in vitro;in vivo)  ViewAnalyzing
4MAZMAZ_HUMANS469GVPVS S QPLPS 35.73%CK2_group Phospho.ELM 7.0 ViewAnalyzing