|Description: Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-bindingprotein) (Alpha-pal).|
Ensembl ID: ENSG00000106459
UniprotKB/SwissProt: NRF1_HUMAN (Q16656)
Function: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.