Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinase CK2a1]
Substrate: NRF1

Description: Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-bindingprotein) (Alpha-pal).

Ensembl ID: ENSG00000106459

UniprotKB/SwissProt: NRF1_HUMAN (Q16656)

Function: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of NRF1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1NRF1NRF1_HUMANS39EHSML S ADEDS 25.65%CK2_group Swiss-Prot 55.0  ViewAnalyzing
2NRF1NRF1_HUMANS44SADED S PSSPE 25.32%CK2_group Swiss-Prot 55.0  ViewAnalyzing
3NRF1NRF1_HUMANS46DEDSP S SPEDT 63.58%CK2_group Swiss-Prot 55.0  ViewAnalyzing
4NRF1NRF1_HUMANS47EDSPS S PEDTS 35.38%CK2_group Swiss-Prot 55.0  ViewAnalyzing
5NRF1NRF1_HUMANS52SPEDT S YDDSD 38.60%CK2_group Swiss-Prot 55.0  ViewAnalyzing