|Description: Proteasome subunit alpha type-3 (EC 22.214.171.124) (Proteasome componentC8) (Macropain subunit C8) (Multicatalytic endopeptidase complexsubunit C8).|
Ensembl ID: ENSG00000100567
UniprotKB/SwissProt: PSA3_HUMAN (P25788)
Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus.