Regulatory Network in Protein Phosphorylation
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Substrate: PSMA3

Description: Proteasome subunit alpha type-3 (EC 3.4.25.1) (Proteasome componentC8) (Macropain subunit C8) (Multicatalytic endopeptidase complexsubunit C8).

Synonyms: PSC8

Ensembl ID: ENSG00000100567

UniprotKB/SwissProt: PSA3_HUMAN (P25788)

Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PSMA3

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PSMA3PSA3_HUMANY161GVSYG Y WGCAI 7.15% Swiss-Prot 55.0 View   
2PSMA3PSA3_HUMANS243KYAKE S LKEED 43.99% Swiss-Prot 55.0 View   
3PSMA3PSA3_HUMANS243KYAKE S LKEED 43.99% HPRD:01463(in vivo)View   
4PSMA3PSA3_HUMANS243KYAKE S LKEED 43.99% HPRD:01463(in vitro)View   
5PSMA3PSA3_HUMANS243KYAKE S LKEED 43.99%CK2_group Phospho.ELM 7.0 ViewAnalyzing
6PSMA3PSA3_HUMANS243KYAKE S LKEED 43.99%CK2a1-rs HPRD:01463(in vitro;in vivo)  ViewAnalyzing
7PSMA3PSA3_HUMANS243KYAKE S LKEED 43.99%CK2a1 HPRD:01463(in vitro;in vivo)  ViewAnalyzing
8PSMA3PSA3_HUMANS250KEEDE S DDDNM 59.67%CK2_group Phospho.ELM 7.0 ViewAnalyzing
9PSMA3PSA3_HUMANS250KEEDE S DDDNM 59.67% Swiss-Prot 55.0 View   
10PSMA3PSA3_HUMANS250KEEDE S DDDNM 59.67% HPRD:01463(in vivo)View