Regulatory Network in Protein Phosphorylation
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Substrate: PTGES3

Description: Prostaglandin E synthase 3 (EC (Cytosolic prostaglandin E2synthase) (cPGES) (Telomerase-binding protein p23) (Hsp90 co-chaperone) (Progesterone receptor complex p23).

Synonyms: P23, TEBP

Ensembl ID: ENSG00000110958

UniprotKB/SwissProt: TEBP_HUMAN (Q15185)

Function: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PTGES3

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PTGES3TEBP_HUMANS113DWEDD S DEDMS 56.04% Swiss-Prot 55.0 View   
2PTGES3TEBP_HUMANS113DWEDD S DEDMS 56.04% HPRD:06138(in vivo)View   
3PTGES3TEBP_HUMANS113DWEDD S DEDMS 56.04%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
4PTGES3TEBP_HUMANS118SDEDM S NFDRF 46.82% Swiss-Prot 55.0 View   
5PTGES3TEBP_HUMANS118SDEDM S NFDRF 46.82%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
6PTGES3TEBP_HUMANS148GADDD S QDSDD 42.77% Swiss-Prot 55.0 View   
7PTGES3TEBP_HUMANS148GADDD S QDSDD 42.77% Phospho.ELM 7.0View   
8PTGES3TEBP_HUMANS151DDSQD S DDEKM 39.05% Swiss-Prot 55.0 View