|Description: Diamine acetyltransferase 1 (EC 188.8.131.52) (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) (Putrescine acetyltransferase)(Polyamine N-acetyltransferase 1).|
Ensembl ID: ENSG00000130066
UniprotKB/SwissProt: SAT1_HUMAN (P21673)
Function: Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm.