|Description: Serine/threonine-protein kinase SRPK2 (EC 184.108.40.206) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRSprotein kinase 2).|
Ensembl ID: ENSG00000135250
UniprotKB/SwissProt: SRPK2_HUMAN (P78362)
Function: Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus.