Regulatory Network in Protein Phosphorylation
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Substrate: TNNT2

Description: Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

Ensembl ID: ENSG00000118194

UniprotKB/SwissProt: TNNT2_HUMAN (P45379)

Function: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
PDB:1J1D
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of TNNT2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1TNNT2TNNT2_HUMANS2----M S DIEEV 47.50%CK2_group Swiss-Prot 55.0 (Similarity) ViewAnalyzing
2TNNT2TNNT2_HUMANT204QKQAQ T ERKSG 40.55%MAP3K5 HPRD:01844(in vitro;in vivo)  ViewAnalyzing
3TNNT2TNNT2_HUMANS208QTERK S GKRQT 56.63%MAP3K5 HPRD:01844(in vitro;in vivo)  ViewAnalyzing
4TNNT2TNNT2_HUMANT213SGKRQ T EREKK 40.83%PKCa HPRD:01844(in vitro)  ViewAnalyzing
5TNNT2TNNT2_HUMANT294GKAKV T GRWK 21.96%PKCa HPRD:01844(in vitro)  ViewAnalyzing