Regulatory Network in Protein Phosphorylation
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Substrate: ANP32A

Description: Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potentheat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclearphosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp)(Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

Synonyms: C15orf1, LANP, MAPM, PHAP1

Ensembl ID: ENSG00000140350

UniprotKB/SwissProt: AN32A_HUMAN (P39687)

Function: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
PDB:2JE0
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ANP32A

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ANP32AAN32A_HUMANS158KEAPD S DAEGY 37.35% Swiss-Prot 55.0 View   
2ANP32AAN32A_HUMANS158KEAPD S DAEGY 37.35%CK2_group Phospho.ELM 7.0 ViewAnalyzing
3ANP32AAN32A_HUMANS204EEEDV S GEEEE 53.46%CK2_group Phospho.ELM 7.0 ViewAnalyzing