Regulatory Network in Protein Phosphorylation
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Substrate: ATF1

Description: Cyclic AMP-dependent transcription factor ATF-1 (Activatingtranscription factor 1) (TREB36 protein).

Ensembl ID: ENSG00000123268

UniprotKB/SwissProt: ATF1_HUMAN (P18846)

Function: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ATF1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ATF1ATF1_HUMANS36QVSSL S ESEES 40.81%CK2a1-rs HPRD:00440(in vitro)  ViewAnalyzing
2ATF1ATF1_HUMANS36QVSSL S ESEES 40.81%CK2_group Phospho.ELM 7.0 ViewAnalyzing
3ATF1ATF1_HUMANS36QVSSL S ESEES 40.81%CK2a1 HPRD:00440(in vitro)  ViewAnalyzing
4ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%CaMK1a HPRD:00440(in vitro)  ViewAnalyzing
5ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%MSK1 HPRD:00440(in vivo)  ViewAnalyzing
6ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%PKACa HPRD:00440(in vitro)  ViewAnalyzing
7ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%MSK1(RSK5) Phospho.ELM 7.0 ViewAnalyzing
8ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%MSK2 HPRD:00440(in vitro)  ViewAnalyzing
9ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%CaMK2g HPRD:00440(in vitro;in vivo)  ViewAnalyzing
10ATF1ATF1_HUMANS63LARRP S YRKIL 35.44%CaMK1 _group Swiss-Prot 55.0  ViewAnalyzing