|Description: Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1).|
Ensembl ID: ENSG00000100290
UniprotKB/SwissProt: BIK_HUMAN (Q13323)
Function: Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Intracytoplasmic membrane; Single-pass membrane protein. Note=Around the nuclear envelope, and in cytoplasmic membranes.