Regulatory Network in Protein Phosphorylation
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Substrate: CD5

Description: T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen T1/Leu-1) (CD5 antigen).

Synonyms: LEU1

Ensembl ID: ENSG00000110448

UniprotKB/SwissProt: CD5_HUMAN (P06127)

Function: May act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.
PDB:2JA4
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CD5

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CD5CD5_HUMANT434FHRNH T ATVRS 27.80%PKCg HPRD:01078(in vitro)  ViewAnalyzing
2CD5CD5_HUMANT434FHRNH T ATVRS 27.80%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
3CD5CD5_HUMANT434FHRNH T ATVRS 27.80%PKCa HPRD:01078(in vitro)  ViewAnalyzing
4CD5CD5_HUMANT434FHRNH T ATVRS 27.80%PKCb HPRD:01078(in vitro)  ViewAnalyzing
5CD5CD5_HUMANT436RNHTA T VRSHA 20.01%PKCb HPRD:01078(in vitro)  ViewAnalyzing
6CD5CD5_HUMANT436RNHTA T VRSHA 20.01%PKCg HPRD:01078(in vitro)  ViewAnalyzing
7CD5CD5_HUMANT436RNHTA T VRSHA 20.01%PKCa HPRD:01078(in vitro)  ViewAnalyzing
8CD5CD5_HUMANT436RNHTA T VRSHA 20.01%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
9CD5CD5_HUMANS439TATVR S HAENP 23.78% Swiss-Prot 55.0 View   
10CD5CD5_HUMANS439TATVR S HAENP 23.78% HPRD:01078(in vitro)View   
11CD5CD5_HUMANS439TATVR S HAENP 23.78% Phospho.ELM 7.0View   
12CD5CD5_HUMANY453HVDNE Y SQPPR 20.89%Lck Phospho.ELM 7.0  ViewAnalyzing
13CD5CD5_HUMANY453HVDNE Y SQPPR 20.89%LCK HPRD:01078(in vitro;in vivo)  ViewAnalyzing
14CD5CD5_HUMANY453HVDNE Y SQPPR 20.89% Swiss-Prot 55.0 View   
15CD5CD5_HUMANY453HVDNE Y SQPPR 20.89%FYN HPRD:01078(in vitro;in vivo)  ViewAnalyzing
16CD5CD5_HUMANS454VDNEY S QPPRN 29.99% HPRD:01078(in vitro)View   
17CD5CD5_HUMANS460QPPRN S RLSAY 35.56% Swiss-Prot 55.0 View   
18CD5CD5_HUMANS460QPPRN S RLSAY 35.56% Phospho.ELM 7.0View   
19CD5CD5_HUMANS460QPPRN S RLSAY 35.56% HPRD:01078(in vitro)View   
20CD5CD5_HUMANY465SRLSA Y PALEG 5.90% HPRD:01078(in vitro)View   
21CD5CD5_HUMANY465SRLSA Y PALEG 5.90% Phospho.ELM 7.0View   
22CD5CD5_HUMANS482MQPDN S SDSDY 42.79%CK2_group Phospho.ELM 7.0 ViewAnalyzing
23CD5CD5_HUMANS482MQPDN S SDSDY 42.79%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
24CD5CD5_HUMANS482MQPDN S SDSDY 42.79%CK2a1 HPRD:01078(in vitro;in vivo)  ViewAnalyzing
25CD5CD5_HUMANS482MQPDN S SDSDY 42.79%CK2a1-rs HPRD:01078(in vitro;in vivo)  ViewAnalyzing
26CD5CD5_HUMANS483QPDNS S DSDYD 47.60%CK2a1-rs HPRD:01078(in vitro;in vivo)  ViewAnalyzing
27CD5CD5_HUMANS483QPDNS S DSDYD 47.60%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
28CD5CD5_HUMANS483QPDNS S DSDYD 47.60%CK2_group Phospho.ELM 7.0 ViewAnalyzing
29CD5CD5_HUMANS483QPDNS S DSDYD 47.60%CK2a1 HPRD:01078(in vitro;in vivo)  ViewAnalyzing
30CD5CD5_HUMANS485DNSSD S DYDLH 39.76%CK2a1-rs HPRD:01078(in vitro;in vivo)  ViewAnalyzing
31CD5CD5_HUMANS485DNSSD S DYDLH 39.76%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
32CD5CD5_HUMANS485DNSSD S DYDLH 39.76%CK2_group Phospho.ELM 7.0 ViewAnalyzing
33CD5CD5_HUMANS485DNSSD S DYDLH 39.76%CK2a1 HPRD:01078(in vitro;in vivo)  ViewAnalyzing
34CD5CD5_HUMANY487SSDSD Y DLHGA 25.10%Lck Phospho.ELM 7.0  ViewAnalyzing
35CD5CD5_HUMANY487SSDSD Y DLHGA 25.10%LCK HPRD:01078(in vitro;in vivo)  ViewAnalyzing
36CD5CD5_HUMANY487SSDSD Y DLHGA 25.10%FYN HPRD:01078(in vitro;in vivo)  ViewAnalyzing