|Description: Histone deacetylase 1 (HD1).|
Ensembl ID: ENSG00000116478
UniprotKB/SwissProt: HDAC1_HUMAN (Q13547)
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.