|Description: High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobilitygroup AT-hook protein 1) (High mobility group protein A1) (Highmobility group protein-R).|
Ensembl ID: ENSG00000137309
UniprotKB/SwissProt: HMGA1_HUMAN (P17096)
Function: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.