|Description: Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor1) (HSTF 1).|
Ensembl ID: ENSG00000185122
UniprotKB/SwissProt: HSF1_HUMAN (Q00613)
Function: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation.