Regulatory Network in Protein Phosphorylation
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Substrate: HSP90AB1

Description: Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

Synonyms: HSP90B, HSPC2, HSPCB

Ensembl ID: ENSG00000096384

UniprotKB/SwissProt: HS90B_HUMAN (P08238)

Function: Molecular chaperone. Has ATPase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
PDB:1QZ2
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of HSP90AB1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1HSP90AB1HS90B_HUMANS226REKEI S DDEAE 39.85% Swiss-Prot 55.0 View   
2HSP90AB1HS90B_HUMANS226REKEI S DDEAE 39.85%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
3HSP90AB1HS90B_HUMANS226REKEI S DDEAE 39.85%CK2_group Phospho.ELM 7.0 ViewAnalyzing
4HSP90AB1HS90B_HUMANS255IEDVG S DEEDD 41.52% HPRD:06763(in vivo)View   
5HSP90AB1HS90B_HUMANS255IEDVG S DEEDD 41.52%CK2_group Phospho.ELM 7.0 ViewAnalyzing
6HSP90AB1HS90B_HUMANS255IEDVG S DEEDD 41.52%CK2a1(CK2 alpha) Phospho.ELM 7.0 ViewAnalyzing
7HSP90AB1HS90B_HUMANS255IEDVG S DEEDD 41.52% Swiss-Prot 55.0 View   
8HSP90AB1HS90B_HUMANS261DEEDD S GKDKK 61.13% Swiss-Prot 55.0 View   
9HSP90AB1HS90B_HUMANS261DEEDD S GKDKK 61.13% HPRD:06763(in vivo)View   
10HSP90AB1HS90B_HUMANS261DEEDD S GKDKK 61.13% Phospho.ELM 7.0View   
11HSP90AB1HS90B_HUMANT297NPDDI T QEEYG 36.60% Swiss-Prot 55.0 View   
12HSP90AB1HS90B_HUMANY305EYGEF Y KSLTN 8.72% Swiss-Prot 55.0 (Similarity)View   
13HSP90AB1HS90B_HUMANY484TQKSI Y YITGE 8.91% Swiss-Prot 55.0 View