|Description: Gamma-interferon-inducible protein Ifi-16 (Interferon-induciblemyeloid differentiation transcriptional activator) (IFI 16).|
Ensembl ID: ENSG00000163565
UniprotKB/SwissProt: IF16_HUMAN (Q16666)
Function: May function as a transcriptional repressor. Could have a role in the regulation of hematopoeitic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53 and the retinoblastoma protein. May be involved in the senescence of prostate epithelial cells.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.