Regulatory Network in Protein Phosphorylation
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Substrate: MAX

Description: Protein max (Myc-associated factor X).

Ensembl ID: ENSG00000125952

UniprotKB/SwissProt: MAX_HUMAN (P61244)

Function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3-K9 histone methyltransferase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
PDB:1AN2
Protein Domain and Phosphorylation Sites: